31 mai 2012

Receptor

Bevacizumab (Avastin ○ R) Bevacizumab (Avastin ○ R, rhuMAb-VEGF, Genetech Inc.) Receptor humanized antibody against vascular endothelial growth factor (VEGF), is currently the treatment of colorectal cancer and breast cancer stage Ⅲclinical studies. VEGF regulate angiogenesis, regulation of vascular permeability and function of anti-apoptotic effects on endothelial cells of neovascularization. Bevacizum ˉ ab monotherapy tumor has made a significant therapeutic effect, can also enhance anti-tumor efficacy of chemotherapy. In the... [Lire la suite]
Posté par tnfalpha à 16:42 - Commentaires [0] - Permalien [#]

12 mai 2012

TNF-alpha 001

TNF tumor cell plasma membrane with a certain period of the First performance ofspecific receptor binding at the cell surface to form a cap gathered into the roomcell, move along microtubules and lysosomes into the cell combined with TNF under the action of lysosomal rupture, releasinglysosomal enzymes resulting in cell autolysis. Clinical has been... [Lire la suite]
Posté par tnfalpha à 16:50 - Commentaires [0] - Permalien [#]