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14 octobre 2012

Putative functions of Desmin

The function of desmin has been deduced through studies in knockout mice, but the underlying mechanism of its action is not known. These possibilities may be the result of interactions with other proteins and not desmin itself. More research needs to...

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14 octobre 2012

Desmin

Desmin is a protein that in humans is encoded by the DES gene.Desmin is a type III intermediate filament found near the Z line in sarcomeres. It was first described in 1976, first purified in 1977, the gene was cloned in 1989, and the first knock-out...

Posté par tnfalpha à 10:54 - Commentaires […] - Permalien [#]

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12 octobre 2012

CCR5-Δ32

CCR5-Δ32 is a deletion mutation of a gene that has a specific impact on the function of T cells.At least one copy of CCR5-Δ32 is found in about (5-14%) of people of Northern European and in those of Northern European descent. There also is a small minority...

Posté par tnfalpha à 16:07 - Commentaires […] - Permalien [#]

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12 octobre 2012

HIV and CCR5

HIV most commonly uses CCR5 and/or CXCR4 as a co-receptor to enter its target cells. Several chemokine receptors can function as viral coreceptors, but CCR5 is likely the most physiologically important coreceptor during natural infection. The normal ligands...

Posté par tnfalpha à 16:06 - Commentaires […] - Permalien [#]

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12 octobre 2012

Function of CCR5

The CCR5 protein belongs to the beta chemokine receptors family of integral membrane proteins. It is a G protein-coupled receptor which functions as a chemokine receptor in the CC chemokine group.The natural chemokine ligands that bind to this receptor...

Posté par tnfalpha à 16:03 - Commentaires […] - Permalien [#]

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11 octobre 2012

CCR5

C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines. This is the process by which T cells are attracted to specific...

Posté par tnfalpha à 10:12 - Commentaires […] - Permalien [#]

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5 octobre 2012

Collection and Panels of Beta2-Microglobulin

Beta2 microglobulin can be determined in urine, serum, or plasma samples. It is not necessary to draw the sample in a fasting state, and no special preparations are necessary. Blood is collected by venipuncture in a red-top tube and centrifuged to separate...

Posté par tnfalpha à 08:31 - Commentaires […] - Permalien [#]

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