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23 novembre 2012

Disease relevance of Apoc2

Furthermore, the decrease of LPL activity in the heart, along with the inhibitory effects of excess APOC2, may contribute to the hypertriglyceridemia observed in apoC-II transgenic mice. Finally, we demonstrate that apolipoprotein C-II in human atheroma co-localizes to regions positive for markers of amyloid and macrophage accumulation.

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