26 novembre 2012
High impact information on BHMT
CBS and BHMT mRNA levels and the hepatic level of S-adenosylmethionine were also increased in the ZDF fa/fa rats. Furthermore, the severity of methionine restriction influenced the magnitude of BHMT induction. Concomitant with methionine restriction, dietary methyl groups were required for high levels of BHMT induction, and a dose-dependent relationship was observed between methyl donor intake and BHMT induction.
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