tnf alpha

16 novembre 2012

AKT

AKT2, also known as Protein Kinase B (PKB), is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription and cell migration. The name Akt does...

Posté par tnfalpha à 17:39 - Commentaires […] - Permalien [#]

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7 novembre 2012

Axokine and CNTF

Axokine is a modified version of human Ciliary neurotrophic factor with a 15 amino acid truncation of the C terminus and two amino acid substitutions, which is three to five times more potent than CNTF in in vitro and in vivo assays and has improved stability...

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7 novembre 2012

Satiety effects of CNTF

In 2001, CNTF was reported that in a human study examining the usefulness of CNTF for treatment of motor neuron disease, CNTF produced an unexpected and substantial weight loss in the study subjects. Further investigation revealed that CNTF could reduce...

Posté par tnfalpha à 15:26 - Commentaires […] - Permalien [#]

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7 novembre 2012

Ciliary neurotrophic factor

CNTF encoded by this gene is a polypeptide hormone and nerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations including astrocytes....

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6 novembre 2012

Entrez Gene summary for CEACAM1

CEACAM1 encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within...

Posté par tnfalpha à 15:12 - Commentaires […] - Permalien [#]

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6 novembre 2012

Source / Purification of CEACAM1

CEACAM1 Antibody detects endogenous levels of total CEACAM1 protein. Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala460 of human CEACAM1 protein. Antibodies are purified by protein...

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6 novembre 2012

CEACAM1

CEACAM1 encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within...

Posté par tnfalpha à 15:11 - Commentaires […] - Permalien [#]

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3 novembre 2012

Post-translational modification of CBP Protein

Methylation of the KIX domain by CARM1 blocks association with CBP. This results in the blockade of CREB signaling, and in activation of apoptotic response By similarity. Phosphorylated upon DNA damage, probably by ATM or ATR. Phosphorylated by CHUK/IKKA...

Posté par tnfalpha à 16:01 - Commentaires […] - Permalien [#]

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3 novembre 2012

CBP Protein Research Areas

The CBP Protein product can be utilized in the following research areas, but not limited to: Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, PKA/PKC Pat...

Posté par tnfalpha à 16:00 - Commentaires […] - Permalien [#]

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3 novembre 2012

Scientific Background of CBP Protein

CBP or CREB-binding protein is a nuclear transcriptional coactivator protein that binds specifically to the PKA-phosphorylated form of the CREB protein. Microinjection of an anti-CBP antiserum into fibroblasts leads to inhibition of transcription from...

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