18 décembre 2012
Disease relevance of Anxa1
In the zymosan peritonitis model, AnxA1 null mice displayed a higher degree (50-70%) of PMN recruitment compared with wild-type littermate mice, and this was associated with reduced numbers of F4/80+ cells . Down-regulation of the anti-inflammatory protein Annexin A1 in cystic fibrosis knock-out mice and patients.
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