20 décembre 2012

Anatomical context of Batroxobin

The right common carotid artery of the dog was perfused with Krebs-Henseleit solution at a constant pressure, 3,4-diaminopyridine (DAP), a selective potassium channel blocker was applied on the adventitia, and the luminal changes were observed with angiography and Batroxobin.
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20 décembre 2012

High impact information on Batroxobin

In conclusion, intraoperative angioscopy provides visual assessment of luminal patency and anastomotic anatomy . Changes in coronary plaque color and morphology by lipid-lowering therapy with atorvastatin: serial evaluation by coronary Batroxobin.
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20 décembre 2012

Batroxobin

Batroxobin is a serine protease derived from the venom of Bothrops atrox. Its molecular weight is approximately 43,000 g/mol−1. This thrombin-like proteolytic enzyme splits the 16 Arg-17 Gly bond in the A(alpha)-chain of fibrinogen, releasing fibrinopeptide A and leading to the clot formation through aggregation of formed of fibrin I monomer or Des-AA-monomer. In contrast to other anti-coagulants, it does not affect the functions of platelets. Hence, Batroxobin is used to determine fibrinogen in plasma, to measure a 'batroxobin... [Lire la suite]
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