25 décembre 2012

BDNF in neuron

Although hippocampal neurons do not express typical LDCV proteins, transfected chromogranins A, B, and brain-derived neurotrophic factor (BDNF) colocalize with VMAT2.
Posté par tnfalpha à 02:09 - Commentaires [0] - Permalien [#]

25 décembre 2012

Expression of BDNF

These factors may act as the eventual repressors for BDNF expression via competition and heterodimerization with phosphorylated CREB, a transcription factor important for BDNF expression. Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons.
Posté par tnfalpha à 02:08 - Commentaires [0] - Permalien [#]
25 décembre 2012

Enzymatic interactions of Bdnf

In contrast, multiple bolus microinjections of BDNF accelerated kindling development and did not affect the level of phosphorylated Trks or TrkB receptors. In contrast to shams, the acutely exercised FPI rats failed to show activity-dependent BDNF upregulation and had significant decreases of phosphorylated synapsin I and total CREB.
Posté par tnfalpha à 02:08 - Commentaires [0] - Permalien [#]