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20 décembre 2012

High impact information on Batroxobin

In conclusion, intraoperative angioscopy provides visual assessment of luminal patency and anastomotic anatomy . Changes in coronary plaque color and morphology by lipid-lowering therapy with atorvastatin: serial evaluation by coronary Batroxobin.
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20 décembre 2012

Batroxobin

Batroxobin is a serine protease derived from the venom of Bothrops atrox. Its molecular weight is approximately 43,000 g/mol−1. This thrombin-like proteolytic enzyme splits the 16 Arg-17 Gly bond in the A(alpha)-chain of fibrinogen, releasing fibrinopeptide...
18 décembre 2012

High impact information on Anxa1

Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor. We have purified two phospholipase A2 inhibitory proteins (Annexin A1) from peritoneal fluid of dexamethasone-treated rats. Dexamethasone induces...
18 décembre 2012

Disease relevance of Anxa1

In the zymosan peritonitis model, AnxA1 null mice displayed a higher degree (50-70%) of PMN recruitment compared with wild-type littermate mice, and this was associated with reduced numbers of F4/80+ cells . Down-regulation of the anti-inflammatory protein...
18 décembre 2012

annexin A1 Mus musculus

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2 décembre 2012

Inflammation with Annexin A1

Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins, and leukotrienes, Annexin A1 may have potential anti-inflammatory activity. Glucocorticoids stimulate production of lipocortin. In this way,...
2 décembre 2012

Function of Annexin A1

Annexin A1 belongs to the annexin family of Ca2+-dependent phospholipid-binding proteins that have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has...
2 décembre 2012

Annexin A1

Annexin A1 also known as lipocortin I is a protein that in humans is encoded by the ANXA1 gene. Annexin-A1 has also been shown to be protective against DNA damage induced by heat in breast cancer cells, adding to the evidence that it has tumor suppressive...
1 décembre 2012

About the Image for Betacellulin

The structure for the small protein Betacellulin that is shown was determined by two-dimensional nuclear magnetic resonance spectroscopy. The species that BTC was taken from was Homo sapiens.This particular molecule of BTC has a formula weight of 5916.9...
1 décembre 2012

Structure of Betacellulin

Betacellulin was originally identified as a growth-promoting factor in mouse pancreatic β-cell carcinoma cell line and has since been identified in humans. Mouse BTC (mBTC) is expressed as a 178-amino acid precursor. The membrane-bound precursor is cleaved...
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