tnf alpha

1 décembre 2012

Betacellulin

Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. Betacellulin is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed...

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29 novembre 2012

Interactions about BMPR1A

BMP's repress WNT signaling to maintain stable stem cell populations. BMPR1A null mice died at embyonic day 8.0 without mesoderm specification, demonstrating its vital role in gastrulation. It has been demonstrated in experiments using dominant negative...

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29 novembre 2012

Function of BMPR1A

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin...

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29 novembre 2012

BMPR1A

The bone morphogenetic protein receptor, type IA also known as BMPR1A is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292. BMPR1A, SMAD4 and PTEN are responsible for Juvenile polyposis syndrome, juvenile...

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26 novembre 2012

Chemical compound and disease context of BHMT

To initiate X-ray crystallographic structural studies, we created a BHMT expression construct for use in Escherichia coli that has a polyhistidine purification tag with no extraneous protein, usually found in commercial vectors, between the tag and protein...

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26 novembre 2012

High impact information on BHMT

CBS and BHMT mRNA levels and the hepatic level of S-adenosylmethionine were also increased in the ZDF fa/fa rats. Furthermore, the severity of methionine restriction influenced the magnitude of BHMT induction. Concomitant with methionine restriction,...

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26 novembre 2012

Disease relevance of BHMT

A plasmid containing the human BHMT cDNA fused in frame to the N terminus of beta-galactosidase was transformed into Escherichia coli, and transformants expressed BHMT activity, an activity that is absent from wild type E. coli. Mutation analysis may...

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23 novembre 2012

High impact information on Apoc2

Overexpression of APOC2 causes hypertriglyceridemia in transgenic mice. In the present studies, initial attempts to demonstrate cAMP-dependent activation of triglyceride lipase using the 1,000 X g supernatant fraction (S1) of mouse heart homogenate were...

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23 novembre 2012

Disease relevance of Apoc2

Furthermore, the decrease of LPL activity in the heart, along with the inhibitory effects of excess APOC2, may contribute to the hypertriglyceridemia observed in apoC-II transgenic mice. Finally, we demonstrate that apolipoprotein C-II in human atheroma...

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23 novembre 2012

APOC2

Apolipoprotein C2 or Apolipoprotein C-II is a protein that in humans is encoded by the APOC2 gene. The protein encoded by this gene is secreted in plasma where it is a component of very low density lipoproteins and chylomicrons. This protein activates...

Posté par tnfalpha à 16:05 - Commentaires […] - Permalien [#]

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