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        <title><![CDATA[tnf alpha]]></title>
        <link>https://tnfalpha.canalblog.com/</link>
        <generator>Overblog - https://www.over-blog.com</generator>
        <description><![CDATA[tnf alpha gene]]></description>
                    <item>
    <title><![CDATA[p16 family]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2013/01/02/26046874.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2013/01/02/26046874.html</guid>
    <pubDate>Wed, 02 Jan 2013 02:26:59 +0100</pubDate>
    <description><![CDATA[Six CDKN2A families had pancreatic cancer . They also show that families with the CDKN2A 113insArg mutation have an increased risk not only of multiple melanomas and pancreatic carcinoma but also of breast cancer. We previously described CDKN2A exon 2... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Disease relevance of CDKN2A]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2013/01/02/26046871.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2013/01/02/26046871.html</guid>
    <pubDate>Wed, 02 Jan 2013 02:26:42 +0100</pubDate>
    <description><![CDATA[Although germline CDKN2A coding mutations cosegregate with melanoma in 25-60% of families predisposed to the disease, there remains a number of mutation-negative families that demonstrate linkage of inherited melanoma to 9p21 markers. High frequency of... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Interactions about p16]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2013/01/02/26046869.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2013/01/02/26046869.html</guid>
    <pubDate>Wed, 02 Jan 2013 02:25:31 +0100</pubDate>
    <description><![CDATA[CDKN2A (gene) has been shown to interact with SERTAD1, CCNG1, Death associated protein 6, P53, E4F1, Cyclin-dependent kinase 4, Cyclin-dependent kinase 6, Mdm2, RPL11 and PPP1R9B. In spite of their structural and functional differences, the CDK inhibitor... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[BCHE in UniProtKB/Swiss-Prot]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2013/01/01/26039448.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2013/01/01/26039448.html</guid>
    <pubDate>Tue, 01 Jan 2013 01:51:26 +0100</pubDate>
    <description><![CDATA[Function: BCHE Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Entrez Gene summary for BCHE]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2013/01/01/26039445.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2013/01/01/26039445.html</guid>
    <pubDate>Tue, 01 Jan 2013 01:51:04 +0100</pubDate>
    <description><![CDATA[Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Drug interaction sites of BCHE]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2013/01/01/26039444.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2013/01/01/26039444.html</guid>
    <pubDate>Tue, 01 Jan 2013 01:50:42 +0100</pubDate>
    <description><![CDATA[Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis. Enzyme-linked immunosorbent assays for acetylcholinesterase (AChE) and for butyrylcholinesterase (BCHE) were markedly more specific than conventional... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Extensiv incorporation of BCHE]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/31/26032807.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/31/26032807.html</guid>
    <pubDate>Mon, 31 Dec 2012 03:22:50 +0100</pubDate>
    <description><![CDATA[BCHE variants (BCHE and CHE2 Loci) associated with erythrocyte acetylcholinesterase inhibition in farmers exposed to pesticides. The findings do not support the premise that inhibitor therapy should target BuChE so as to prevent increased levels of BuChE... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Anatomical context of BCHE]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/31/26032805.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/31/26032805.html</guid>
    <pubDate>Mon, 31 Dec 2012 03:22:35 +0100</pubDate>
    <description><![CDATA[Transient expression of BCHE-reporter gene constructs showed that a 194-bp fragment of the 5'-flanking region of human BCHE and a 570-bp fragment of rabbit BCHE were sufficient for promoting chloramphenicol acetyltransferase activity in HeLa cells. The... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[BCHE and BuchE]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/31/26032804.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/31/26032804.html</guid>
    <pubDate>Mon, 31 Dec 2012 03:22:16 +0100</pubDate>
    <description><![CDATA[An atypical form of butyrylcholinesterase or the absence of its activity leads to prolonged apnea following administration of the muscle relaxant suxamethonium. BCHE and obesity in individuals with the CHE2 C5+ and CHE2 C5- phenotypes. In this retrospective... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Activity of BCHE]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/30/26021732.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/30/26021732.html</guid>
    <pubDate>Sun, 30 Dec 2012 02:32:55 +0100</pubDate>
    <description><![CDATA[Protein concentration and acetylcholinesterase (AChE) and butyrylcholinesterase (BCHE) activities were assayed in the cerebrospinal fluid (CSF) of 26 healthy normal subjects (20-86 years old), 27 patients with dementia of the Alzheimer type (DAT), and... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Psychiatry related information on BCHE]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/30/26021731.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/30/26021731.html</guid>
    <pubDate>Sun, 30 Dec 2012 02:32:38 +0100</pubDate>
    <description><![CDATA[In Alzheimer's disease, BCHE may have thus acquired an inverse role to that of AChE by adopting imperfect amphipathic characteristics of its C terminus. Our results point to a possible association between an abnormal lipid metabolism and the BChE activity... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Restriction analysis of BCHE]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/30/26021730.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/30/26021730.html</guid>
    <pubDate>Sun, 30 Dec 2012 02:32:20 +0100</pubDate>
    <description><![CDATA[PvuII restriction analysis and DNA blot hybridization of the amplified ACHE and BCHE sequences demonstrated apparent aberrations in both genes, suggesting that malfunctioning of modified, partially amplified cholinesterase genes may be involved in the... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Entrez Gene summary for BAX]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/29/26014334.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/29/26014334.html</guid>
    <pubDate>Sat, 29 Dec 2012 01:30:04 +0100</pubDate>
    <description><![CDATA[The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BAX forms a heterodimer with BCL2,... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[BAX in immunoblotting]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/29/26014333.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/29/26014333.html</guid>
    <pubDate>Sat, 29 Dec 2012 01:29:48 +0100</pubDate>
    <description><![CDATA[Significantly highernumbers of BAX positive hepatocytes were observed in HBsAg positive patients when compared to control groups. Immunoblotting revealed that BAX transfectants expressed a mean of 10-fold increased levels of BAX compared with neo-transfected... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Analytical, diagnostic and therapeutic context of BAX]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/29/26014331.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/29/26014331.html</guid>
    <pubDate>Sat, 29 Dec 2012 01:29:33 +0100</pubDate>
    <description><![CDATA[In 47 patients with thyroid tumours (14 follicular and 3 papillary carcinomas, 14 adenomas and 16 goitres), the DNA was screened for mutations of BAX (exon 1-6) and p53 (exon 5-8) by single-strand conformation polymorphism polymerase chain reaction (SSCP-PCR).... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Cytotoxicity of BAX]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/28/26006648.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/28/26006648.html</guid>
    <pubDate>Fri, 28 Dec 2012 03:06:29 +0100</pubDate>
    <description><![CDATA[The cytotoxicity of paclitaxel, vincristine, and doxorubicin was significantly enhanced in BAX transfectants compared with control clones, whereas the cytotoxicity profile of carboplatin, etoposide, and hydroxyurea was unchanged. The inhibitor benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Associations of BAX with chemical compounds]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/28/26006647.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/28/26006647.html</guid>
    <pubDate>Fri, 28 Dec 2012 03:06:03 +0100</pubDate>
    <description><![CDATA[Coexpression of BAD and NOXA killed wild-type but not Bax, Bak doubly deficient cells or Puma deficient cells with Bim knockdown, indicating that activator BH3-only molecules function downstream of inactivator BH3-only molecules to activate BAX-BAK. These... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[BAX treatment]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/28/26006646.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/28/26006646.html</guid>
    <pubDate>Fri, 28 Dec 2012 03:05:44 +0100</pubDate>
    <description><![CDATA[Interestingly, LDFRT treatment in both cell lines with or without Paclitaxel down-regulated nuclear factor kappa B activity and BCL-2 protein expression and simultaneously up-regulated BAX protein. Recent genetic studies with fibroblasts derived from... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[High impact information on BAX]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/27/26000280.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/27/26000280.html</guid>
    <pubDate>Thu, 27 Dec 2012 02:31:32 +0100</pubDate>
    <description><![CDATA[Moreover, BCL-XL, BCL-2, and BAX can form ion-conductive pores in artificial membranes [5]. The percentage of myocytes labeled with BCL2 (which protects cells against apoptosis) was 1.8 times as high in the hearts of patients with cardiac failure as in... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Elevated BAX]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/27/26000279.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/27/26000279.html</guid>
    <pubDate>Thu, 27 Dec 2012 02:31:17 +0100</pubDate>
    <description><![CDATA[Surprisingly, we observed elevated BAX levels in patients with thyroid carcinomas compared with patients with adenomas (unpaired t-test: p<0.05) or with goitres (p<0.02). We conclude that BAX expression may represent a prognostic indicator for patients... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Disease relevance of BAX]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/27/26000278.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/27/26000278.html</guid>
    <pubDate>Thu, 27 Dec 2012 02:31:00 +0100</pubDate>
    <description><![CDATA[Loss of BAX also renders colorectal cancer cells resistant to TRAIL/Apo2L-mediated radiosensitization. These same v-BCL-2 proteins cooperate with loss of retinoblastoma protein and p53 tumor suppressor function, by inactivating the BAX and BAK apoptotic... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[mRNA of BDNF]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/26/25994195.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/26/25994195.html</guid>
    <pubDate>Wed, 26 Dec 2012 01:55:40 +0100</pubDate>
    <description><![CDATA[In situ hybridizations for BDNF and trkB mRNA revealed that virtually all CSNs express trkB, whereas only half of them express BDNF. As revealed with 5-HT immunocytochemistry, BDNF infusions into the neocortex of intact (non-PCA-lesioned) rats caused... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Analytical, diagnostic and therapeutic context of Bdnf]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/26/25994194.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/26/25994194.html</guid>
    <pubDate>Wed, 26 Dec 2012 01:55:25 +0100</pubDate>
    <description><![CDATA[The increase in BDNF mRNA was mediated by a selective activation of the BDNF exon IV promoter and adrenalectomy attenuated this increase by 50%. In bioassays, BDNF and NT-3, but not NGF, at physiological concentrations induced neurite outgrowth from the... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[Immunoreactivity  of BDNF]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/26/25994191.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/26/25994191.html</guid>
    <pubDate>Wed, 26 Dec 2012 01:55:09 +0100</pubDate>
    <description><![CDATA[The distribution of BDNF-induced neuropeptide Y immunoreactivity is similar to the pattern observed in animals submitted to hippocampal kindling, with the exception of mossy fibres which only become immunoreactive following seizure activity. We found... ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
    </item>
                    <item>
    <title><![CDATA[BDNF in neuron]]></title>
    <link><![CDATA[https://tnfalpha.canalblog.com/archives/2012/12/25/25989766.html]]></link>
    <guid>https://tnfalpha.canalblog.com/archives/2012/12/25/25989766.html</guid>
    <pubDate>Tue, 25 Dec 2012 02:09:05 +0100</pubDate>
    <description><![CDATA[Although hippocampal neurons do not express typical LDCV proteins, transfected chromogranins A, B, and brain-derived neurotrophic factor (BDNF) colocalize with VMAT2. ]]></description>
        <dc:creator><![CDATA[tnfalpha]]></dc:creator>
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