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29 septembre 2012

Beta2-Microglobulin Interpretation

Interpretation depends on the specific clinical indication and context. Low serum levels of beta2 microglobulin essentially indicate decreased disease activity in conditions for which beta2 microglobulin is used as a prognostic marker (multiple myeloma,...
Posté par tnfalpha à 13:37 - Commentaires […] - Permalien [#]

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26 septembre 2012

Reference Range of beta2 microglobulin

Serum and plasma beta2 microglobulin values have emerged as markers for the activation of the cellular immune system, as well as a tumor marker in certain hematologic malignancies. Urine beta2 microglobulin values indicate renal filtration disorders....
Posté par tnfalpha à 14:54 - Commentaires […] - Permalien [#]

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24 septembre 2012

Clinical significance of Beta-2 microglobulin

In patients on long-term hemodialysis, it can aggregate into amyloid fibers that deposit in joint spaces, a disease known as dialysis-related amyloidosis.Mice models deficient for the β2 microglobulin gene have been engineered. These mice demonstrate...
Posté par tnfalpha à 09:00 - Commentaires […] - Permalien [#]

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18 septembre 2012

Structure and function of Beta-2 microglobulin

β2 microglobulin lies lateral to the α3 chain on the cell surface. Unlike α3, β2 has no transmembrane region. Directly above β2 (i.e. away from the cell) lies the α1 chain, which itself is lateral to the α2.β2 microglobulin associates not only with the...
Posté par tnfalpha à 16:08 - Commentaires […] - Permalien [#]

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13 septembre 2012

beta2 microglobulin

β2 microglobulin lies lateral to the α3 chain on the cell surface. Unlike α3, β2 has no transmembrane region. Directly above β2 (i.e. away from the cell) lies the α1 chain, which itself is lateral to the α2.β2 microglobulin associates not only with the...
Posté par tnfalpha à 14:25 - Commentaires […] - Permalien [#]

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