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31 décembre 2012

Extensiv incorporation of BCHE

BCHE variants (BCHE and CHE2 Loci) associated with erythrocyte acetylcholinesterase inhibition in farmers exposed to pesticides. The findings do not support the premise that inhibitor therapy should target BuChE so as to prevent increased levels of BuChE...

Posté par tnfalpha à 03:22 - Commentaires […] - Permalien [#]

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31 décembre 2012

Anatomical context of BCHE

Transient expression of BCHE-reporter gene constructs showed that a 194-bp fragment of the 5'-flanking region of human BCHE and a 570-bp fragment of rabbit BCHE were sufficient for promoting chloramphenicol acetyltransferase activity in HeLa cells. The...

Posté par tnfalpha à 03:22 - Commentaires […] - Permalien [#]

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31 décembre 2012

BCHE and BuchE

An atypical form of butyrylcholinesterase or the absence of its activity leads to prolonged apnea following administration of the muscle relaxant suxamethonium. BCHE and obesity in individuals with the CHE2 C5+ and CHE2 C5- phenotypes. In this retrospective...

Posté par tnfalpha à 03:22 - Commentaires […] - Permalien [#]

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30 décembre 2012

Activity of BCHE

Protein concentration and acetylcholinesterase (AChE) and butyrylcholinesterase (BCHE) activities were assayed in the cerebrospinal fluid (CSF) of 26 healthy normal subjects (20-86 years old), 27 patients with dementia of the Alzheimer type (DAT), and...

Posté par tnfalpha à 02:32 - Commentaires […] - Permalien [#]

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30 décembre 2012

Psychiatry related information on BCHE

In Alzheimer's disease, BCHE may have thus acquired an inverse role to that of AChE by adopting imperfect amphipathic characteristics of its C terminus. Our results point to a possible association between an abnormal lipid metabolism and the BChE activity...

Posté par tnfalpha à 02:32 - Commentaires […] - Permalien [#]

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30 décembre 2012

Restriction analysis of BCHE

PvuII restriction analysis and DNA blot hybridization of the amplified ACHE and BCHE sequences demonstrated apparent aberrations in both genes, suggesting that malfunctioning of modified, partially amplified cholinesterase genes may be involved in the...

Posté par tnfalpha à 02:32 - Commentaires […] - Permalien [#]

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29 décembre 2012

Entrez Gene summary for BAX

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BAX forms a heterodimer with BCL2,...

Posté par tnfalpha à 01:30 - Commentaires […] - Permalien [#]

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29 décembre 2012

BAX in immunoblotting

Significantly highernumbers of BAX positive hepatocytes were observed in HBsAg positive patients when compared to control groups. Immunoblotting revealed that BAX transfectants expressed a mean of 10-fold increased levels of BAX compared with neo-transfected...

Posté par tnfalpha à 01:29 - Commentaires […] - Permalien [#]

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29 décembre 2012

Analytical, diagnostic and therapeutic context of BAX

In 47 patients with thyroid tumours (14 follicular and 3 papillary carcinomas, 14 adenomas and 16 goitres), the DNA was screened for mutations of BAX (exon 1-6) and p53 (exon 5-8) by single-strand conformation polymorphism polymerase chain reaction (SSCP-PCR)....

Posté par tnfalpha à 01:29 - Commentaires […] - Permalien [#]

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28 décembre 2012

Cytotoxicity of BAX

The cytotoxicity of paclitaxel, vincristine, and doxorubicin was significantly enhanced in BAX transfectants compared with control clones, whereas the cytotoxicity profile of carboplatin, etoposide, and hydroxyurea was unchanged. The inhibitor benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl...

Posté par tnfalpha à 03:06 - Commentaires […] - Permalien [#]

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