CYP24A1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and
other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically
active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme
plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants
encoding different isoforms have been found for this gene.